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- UID
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- 性别
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- 2016年
- 帖子
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- 2013-4-8
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个人简历:
颜振宁,女,博士,教授,硕士研究生导师。简历:1992年获河南师范大学学士学位,1996年获河南师范大学溶液化学硕士学位,1999年7月获天津大学化学工艺学博士学位,同年到郑州大学任教;2000-2003年在郑州大学化学博士后工作站从事博士后研究。2001年被评为郑州大学青年骨干教师,2004年被评为河南省青年骨干教师,2007年获得河南省优秀青年科技专家称号。主持了国家自然科学基金面上基金项目2项,河南省杰出青年基金1项,河南省青年骨干教师基金和河南省自然科学基金资助课题多项,参加5项国家自然科学基金面上基金项目和1项国家教育部优秀年轻教师基金项目的研究工作。在国内外期刊上发表论文60余篇,5项科技成果通过省级鉴定,其中两项获河南省科技进步一等奖。9篇论文获河南省自然科学优秀论文一等奖。
联系电话:13643710678 邮箱:yanzzn@zzu.edu.cn
研究方向:
1.生物小分子与有机电解质相互作用的功能溶液化学研究
氨基酸和小肽具有很强的活性、多样性和重要的生物学功能,它们对人体的生命活动具有非常重要的意义。水溶液是生物分子的主要溶剂环境,其中含有许多内源性和外源性物质,这些物质对生物分子的构型和特性有很大的影响,其中电解质的影响在生物物质的物理化学性质的研究中是一个十分重要的课题。我们的研究着眼于生物小分子(例如氨基酸和小肽)与功能有机电解质(简单有机电解质、离子型表面活性剂、离子液体等)之间的相互作用。研究手段以热力学和光谱学技术为主。该研究为了解生理学体系中有机电解质对肽和氨基酸生物活性的影响以及有机电解质的科学使用提供线索。
2.功能材料
离子选择性电极(ISEs)是近十多年来在电位法领域里发展起来的一种新的测试工具,它可以通过简单的电位测量直接测定溶液中某一离子的活度。离子选择性电极目前还是发展中的一门新技术,除少数品种较为成熟外,多数还不够成熟,现阶段,还面临着改进电极的选择性,提高测量精度,研制新的品种以及有关基础理论的研究等问题。我们的研究拟以各种新型有机化合物作为离子选择电极高分子膜的功能材料,制备对某些离子响应的选择电极,用于水质、土壤、食品中相关离子的检测。该项目涉及有机化学和电分析化学的前沿领域,具有重要的基础理论研究意义,在环境保护等方面具有实际应用价值。
承担的主要科研项目:
2016-2019,含药物活性组分的离子液体(API-ILs)基础物理化学性质及其与生物小分子间相互作用的研究,国家自然科学基金,编号:21573199
2009-2010,小肽与有机电解质之间相互作用的热力学和谱学研究,国家自然科学基金,编号:20973158
2005-2007,蛋白质及其模型化合物与有机电解质的相互作用及其生物物理化学性质研究,河南省杰出青年科学基金
2005-2007,蛋白质模型化合物与有机电解质的相互作用及其生物物理化学性质研究,河南省高等学校青年骨干教师资助计划项目
2010-2011,小肽与有机电解质之间弱相互作用的研究,河南省自然科学基金,编号:102300410051
2014-2015,以含酰腙基团的苯并咪唑类化合物为载体的毒性重金属离子选择电极的研制及应用,河南省科技攻关项目,编号:142102310336
2002-2004氨基酸在表面活性剂和有机电解质水溶液中的热力学和谱学研究,河南省教育厅自然科学基金,编号:20021500005
2003-2005,小肽与羧酸钠相互作用的热力学和谱学研究,河南省教育厅自然科学基金,编号:20031500372005-2007,以酰胺型有机化合物为载体的离子选择电极的研究,河南省教育厅自然科学基金,编号:200510459014
2006-2008,双(二硫代氨基甲酸酯)的合成及其作为离子选择电极载体的研究,河南省教育厅自然科学基金,编号:2006150031
部分代表论文:
Zhenning Yan*, Xiangli Wen, Yunxia Kang, Shuangyan Zhang, Shuangyan Wu,Volumetric and conductometric studies on the interactions of dipeptides with potassium perfluoroalkanesulfonate in aqueous solution at different temperatures,J. Chem. Thermodyn., 2016, 93, 172-178Shuangyan Wu, Masanori Tachiya, Zhenning Yan*, An improved procedure for determination of the mean aggregation number of micelles, Spectrochimica Acta Part A 138 (2015) 807–810
Zhenning Yan*, Shuangyan Wu, Qi Pan, Rui Geng, Bixin Gu, Jianji Wang, Interactions of dipeptides with Triton X-100 in aqueous solution: A volumetric and spectroscopic study, J. Chem. Thermodynamics, 2014, 71, 112–117
Zhenning Yan*, Rui Geng Bixin Gu, Qi Pan, Jianji Wang, Densities, electrical conductances, and spectroscopic properties of glycyl dipeptide + ionic liquid ([C12mim]Br) + water mixtures at different temperatures, Fluid Phase Equilibria, 2014, 367, 125–134
Zhenning Yan*, Haixia Wang, CuiyingXu, Xiangli Wen, Bixin Gu Preparation of a new aluminum (III) selective electrode based on a hydrazone-containing benzimidazole derivative as a neutral carrier, Journal of Molecular Liquids, 2014, 190, 185–189
Zhenning Yan*, Shuangqiang Wang, Haixia Wang, Shuangyan Wu, Bismuth (III) PVC membrane ion selective electrodes based on two compounds: Acylhydrazone and thiosemicarbazone with 1,3,4-thiadiazole, Materials Science and Engineering C, 2013, 33, 2562–2568
Zhenning Yan*, Yanqi Lu, Haixia Wang, Shuangyan Wu, Bangtun Zhao, A heterocycle functionalizedp-tert-butylcalix[4]arene as a neutral carrier for silver (I) ion-selective electrode, Journal of Molecular Liquids, 2013, 183, 72 –78
Zhenning Yan*, Ruili Liu, Shuangyan Wu, Xiangru Bai, Jianji Wang, Effect of temperature on the interactions of glycyl dipeptides with sodium perfluorooctanoate in aqueous solution: Volumetric, conductometric, and spectroscopic study, J. Chem. Thermodynamics, 2013, 57, 360–366
Zhenning Yan*, Xiangru Bai, Ruili Liu, Shuangyan Wu, Jianji Wang, Effect of dipeptides on the micellization and thermodynamic parameters of sodium dodecyl sulfonate: Conductometric andfl uorimetric studies, Journal of Molecular Liquids, 2013, 177, 78 –84
Zhenning Yan*, Yuanchao Pei, Jing Fan, Shuangqiang Wang, Jianji Wang, Selective electrodes for [PF6]? and [BF4]? anions based on the associates formed by ionic liquid and cationic dyes, Materials Science and Engineering C, 2013, 33, 356–361
Zhenning Yan*, Xiaolan Wang, Xiangru Bai, Shuangqiang Wang, Jianji Wang, Volumetric, conductometric and fluorescence probe studies of interactions between glycyl dipeptides and sodium caprylate in aqueous media, J. Chem. Thermodynamics, 2012, 52, 89–94
Zhenning Yan*, Junying Dan, Liqin Li, Shuangqiang Wang, Bangtun Zhao, Lead (II) ion-selective membrane electrodes based on four nitrogen-containing heterocyclic thioethers, Sensor Letters, 2012, 10, 1–9.
Zhenning Yan*, Xia Li, Yan Xu, Baoxian Ye, Amide and acyl-hydrazine functionalized calix[4]arenes as carriers for hydrogen phosphate selective electrodes, Electroanaysis, 2007, 19, 958-963.
Zhenning Yan*, Yanqi Lu, Xia Li, Silver ion-selective electrodes based on bis(dialkyldithiocarbamates) as neutral ionophores, Sens. Actuators B: Chem., 2007, 122, 174-181.
Hao Zheng, Zhenning Yan*, Huimin Dong, Baoxian Ye, Simultaneous determination of lead and cadmium at a glassy carbon electrode modified with Langmuir-Blodgett film of p-tert-butylthiacalix[4]arene, Sens. Actuators B: Chem., 2007, 120, 603-609.
Zhenning Yan*, Qian Zhang, WeiWei Li, Jianji Wang, Effect of temperature on the interactions of glycyl dipeptides with sodium dodecyl sulfate in aqueous solution: a volumetric, conductometric, and fluorescence probe study, J. Chem. Eng. Data, 2010, 55, 3560-3566.
Zhenning Yan*, Yang Zhao, Ronghua Xing, Xiaoge Wang, Jianji Wang,Volumetric and conductometric behavior at T=298.15 K of 2-[(2-aminoacetyl)amino]acetic acid, 2-[(2-aminoacetyl)amino]-3-methylbutanoic acid, and (2S)-2-[(2-aminoacetyl)amino]-4-methylpentanoic acid with sodium hexanoate, J. Chem. Eng. Data, 2010, 55, 759-764.
Zhenning Yan*, Xiaoge Wang, Ronghua Xing, Jianji Wang, Interactions of some glycyl dipeptides with sodium butyrate in aqueous solutions at 298.15 K: a volumetric and conductometric study, J. Chem. Eng. Data, 2009, 54, 1787-1792
Zhenning Yan*, Weiwei Li, Qian Zhang, Xiaoge Wang, Jianji Wang, Effect of sodium caproate on the volumetric and conductometric properties of glycyl-L-glutamine and L-alanyl-L-glutamine in aqueous solution at 298.15 K, Fluid Phase Equilibria, 2011, 301, 156-162
Zhenning Yan*, Qian Zhang, Weiwei Li, Xiaoge Wang, Jianji Wang, Effect of sodium caproate on the volumetric and conductometric properties of glycyl-L-glutamine and L-alanyl-L-glutamine in aqueous solution at 298.15 K,Fluid Phase Equilibria, 2011, 301, 156-162.
Zhenning Yan*, Ximeng Sun, WeiWei Li, Yu Li, Jianji Wang, Interactions of glutamine dipeptides with sodium dodecyl sulfate in aqueous solution measured by volume, conductivity, and fluorescence spectra, J. Chem. Thermodyn., 2011, 43, 1468-1474
Zhenning Yan*, Xiaoge Wang, Ronghua Xing, Jianji Wang, Volumetric and conductometric studies on the interactions of dipeptides with sodium acetate and sodium butyrate in aqueous solutions at T = 298.15 K, J. Chem. Thermodyn., 2009, 41(12), 1343-1349
Zhenning Yan*, Yu Li, Xiaolan Wang, Junying Dan, Jianji Wang, Effect of glycyl dipeptides on the micellar behavior of gemini surfactant: A conductometric and fluorescence spectroscopic study, Journal of Molecular Liquids, 2011, 161, 49-54 |
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